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将针对牛的tau的LacZ载体和一个floxed neo片段插入到删除了39个碱基，包括起始甲硫氨酸密码子以及信号肽的6个氨基酸编码密码子的第1个外显子中。通过小鼠的germ-line和Cre介导的重组来去除neo片段。通过β-半乳糖苷酶试验确认了lacZ的表达。这是由于插入位置导致的无功能性等位基因。(来源：J:132854)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
