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中文
这个转基因是通过从CD-1基因组cosmid克隆cos2W3a的10-kb小鼠基因组DNA片段构建的，它包含了Hoxc11编码区域，前后各有2kb和5kb的非编码DNA。在exon 1的Eag1限制酶位点插入了大肠杆菌lacZ的编码序列，替换了内部的Eag1DNA片段。在11.5-13.5dpc胚胎中，通过Xgal染色检测到的转基因β-半乳糖苷酶表达，再现了体内HOXC11在后肢和后肢近端前肢的表达情况。（来源：J:61447）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
