在int-6插入了一段frt-flanked和floxed的neo cassette,并在intron 7中增加了一个loxP位点。通过 germ-line的flp介导重组,neo cassette被移除,从而产生了含有floxed exon 7的转基因。(来源:J:130978)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count