Phox2b^tm2Jbr

Exon 3 was replaced with an exon 3 that contained a 7 alanine expansion of a 20-residue polyalanine chain, mimicking a mutatation found in some congenital central hypoventilation syndrome (CCHS) patients. A floxed neo cassette was also inserted downstream of exon 3. (J:131365)