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中文
将包含人类TATA盒结合蛋白(TBP)的13个polyQ重复扩张的转基因构建，通过小鼠Prion蛋白驱动器，注入到FVB/N雌鼠的受精卵中。建立了TBP-13Q的转基因创始系。 Western blot分析无法分辨野生型和突变型TBP蛋白。4个月大的大脑中未检测到免疫反应性的TBP蛋白。(来源：J:130775)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
