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中文
在小鼠胚胎干细胞（ES）系中，通过RMCE技术，将单个密码子的W298A变异插入了内源性Ptf1a基因座，使用了Ptf1atm1Mgn这一载体。交换载体包含来自129小鼠基因组DNA的SalI-SalI区段的Ptf1a基因，其中第298位的色氨酸（TGG）被PCR突变替换为甘氨酸（GCG）。（来源：J:125691）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
