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中文
在第14个内含子插入了一个floxed neo cassette，然后在第15个内含子额外加入了loxP位点。通过Cre介导的重组，移除了neo cassette和exon 15。产生的蛋白质产品缺少包含ATM结合域的最后24个氨基酸。通过Western blot在小鼠胚胎成纤维细胞提取物中确认了缩短蛋白产物的存在。（来源：J:129762）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
