在该位点进行了一次点突变,导致在C末端激酶域的保守DFG序列由DFG变为AFG。在翻译终止密码子后加入了C末端的Myc抗原标签,并在3' UTR插入了一个可删除的IRE斯-lacZ-geo元件。(来源:J:109024)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
43
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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