这个hIGFBP-1转基因(来自人类cosmid克隆)包含了IGFBP1基因的完整结构,以及所有驱动适当组织特异性和调节性基因表达的cis作用序列。创始小鼠(line c1:2-2)与CBA/Ca进行了杂交,结果显示转基因拷贝数在8到20之间。(来源:J:128964)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL and CBA
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1
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5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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