在exon 2的190bp上游和220bp下游插入了LoxP位点,同时在exon 2之后插入了带有FRT标记的诺卡因 cassette。通过基因组PCR确认了生殖细胞的遗传。检测到LoxP位点或neocassette的存在并未影响基因表达。(来源:J:128713)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
插入
--
1
12
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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