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中文
使用了一个携带人类APOE*2基因(11kb基因片段，包括内源性启动子)和APOCl基因与它对应假基因之间的间隔区，包含推测的肝调控元件(HCR，肝控区域)的构建，用于生成转基因小鼠。人类APOE*2突变特征为Arg158Cys的氨基酸替换。Northern blot结果显示，这个转基因在肝脏中表达。(来源：J:37473)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
