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中文
一段人类cDNA，编码RET的短型（1072个氨基酸）亚型，通过PCR被改造，加入了RET MEN2B突变（Met918Thr）。这个突变的cDNA被插入到人类DBH启动子下游，长度为5.8kb。构建中，在转录起始点和突变cDNA之间，包含猪胰岛素前体基因的首内含子（+13至+183nt）。3'端插入了来自小鼠protamine 1基因的polyadenylation位点。这条转基因线有260个拷贝。（来源：J:108163）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
