2 independent constructs consisting of a 600 bp fragment of the 5' sequences driving the H2-Ead and a 600 bp fragment of 5' sequence driving the H2-Eb1b gene were coinjected into fertilized pronuclei. Four founders with germline transmission were identified and 3 (187-1, 187-7, and 190-5) were further studied. 187-7 (male) was chosen as representative, since it apparently characterized most thoroughly. (J:127706)