一段包含4个外显子,编码1038到1198氨基酸的2kb区域被替换为β-珠蛋白/PGK-neo插入片段。通过 Western blot 分析确认没有蛋白质产物产生。(来源:J:127720)
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A 2 kb region containing 4 exons that encode amino acids 1038 to 1198 was replaced with a beta-globin/PGK-neo cassette. The absence of protein product was confirmed by western blot analysis. (J:127720)