将包含Neo和TK选择标记的删除 cassette 送入了基因的第二个内含子,并在第四内含子中插入了一个第三个loxP位点。短暂的Cre表达后,筛选出了删除了选择 cassette 但保留了3号和4号外显子由loxP位点环绕的克隆。PCR确认了loxP位点的插入。(来源:J:127458)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部