这个转基因包含了由一个双突变的人类SNCA,其中第30位的Pro被Ala替换为A30P,第53位的Thr被Ala替换为A53T,这些改变是在一个鼠的酪氨酸羟化酶启动子的调控下进行的。表达在大脑中可检测到(来源:J:127708)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Applicable
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插入
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1
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4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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