从3号外显子到6号外显子之间有loxP位点,然后在3号外显子5'端插入了由frt位点包裹的neo cassette。在与Gt(ROSA)26Sortm1(FLP1)Dym小鼠杂交后,通过Flp介导的重组移除了neo cassette。通过Southern blot检测来确认这些插入。(来源:J:126501)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入
--
1
2
33

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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