Log In|Sign Up
中文
在loxP位点附近，插入了含氨苄西林抗性基因座和一段人类基因片段，其中第248位的酪氨酸被替换为精氨酸(等位基因为p.R248W)。这个替换涉及了 intron 4 至 10 的区域。随后通过Cre介导的重组移除了neo cassette。通过Southern blot和序列分析确认了这些突变的存在。(来源：J:126497)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
