一个敲除型新霉素抗性基因座被放置在第5外显子附近,另一个loxP位点则位于间隔的内含子中。随后通过转录Cre重组酶的暂时表达,移除了新霉素抗性基因座,使得第5外显子被loxP位点所 flank(来源:J:125953)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
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1
2
43

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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