包含人类CD2启动子,驱动表达小鼠Myb和果蝇Engrailed蛋白2-298氨基酸序列的转基因,以反向方式随机插入到第一个内含子中。这种插入导致正常转录本表达水平的增加。插入通过Southern blot分析得到了确认。(来源:J:125805, J:126456)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(CBA x C57BL/10)F1
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插入
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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