在转录起始密码子下游的一个0.5kb基因组片段被替换了 neo-mycin 选择子 cassette。对全脑来源的RNA进行Northern blot分析后,发现纯合子小鼠中没有可检测到的转录本。 Western blot分析则表明,纯合子小鼠脑提取物中未检测到编码蛋白。(来源:J:38582)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv-Gpi1c
Targeted
插入,基因内删除
--
1
8
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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