在通过和Tg(ACTB-cre)13Miya小鼠杂交,随后通过Cre介导的删除,Exon 21被移除了,这产生了一个框架错位的缺失。蛋白产物的缺失通过在肺、胸腺、大脑、脾和胰腺的蛋白质提取物中进行 Western blot 来验证。(来源:J:126164)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
基因内删除
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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