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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(Tcrb51-11.5)AR1251Ayr
Alias:
Tg(Tcrb-V6-Tcrb-D-Tcrb-J)AR1251Ayr
TCliB
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基础信息
表型特征
文献报道
TCRβ构建包含从hCLIP:I-Ab特异性的T细胞杂交瘤51-11.5克隆出的Vβ6-Dbeta1-Jbeta2.2片段。这个片段被微注射到C57BL/6 x DBA/2的F2胚胎中,建立了AR1251这一突变品系(参考文献J:125548)。
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3760400
(C57BL/6 x DBA/2)F1
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5
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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