从ATG起始密码子到exon 2的60%编码区域被替换成lacZ和floxed neo元件。小鼠与B6-Cre小鼠杂交以去除neo cassette。通过舌组织匀浆的Western blot分析,确认了蛋白产物的存在(来源:J:125325)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6
Targeted
插入,基因内删除
--
1
5
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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