这个转基因载体包含了从一个B10.A-H2/SgSnJMis基因组DNA文库中提取的,包含Cyp21a1基因和大约700kb5'上游DNA的3.9kb基因组DNA片段,其驱动Cyp21a1蛋白(Cytochrome P450, family 21, subfamily a, polypeptide 1)的表达。据Southern blot分析,估计这个转基因在该品系的基因组中整合了5拷贝。(来源:J:20978)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/10SnSlc
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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