这个转基因载体包含了从一个B10.A-H2/SgSnJMis基因组DNA文库中提取的,包含Cyp21a1基因和大约700kb5'上游DNA的3.9kb基因组DNA片段,其驱动Cyp21a1蛋白(Cytochrome P450, family 21, subfamily a, polypeptide 1)的表达。据Southern blot分析,估计这个转基因在该品系的基因组中整合了5拷贝。(来源:J:20978)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count