在第3外显子,包含起始密码子的区域被替换了 neo cassette。通过脑匀浆和突触前密度区域的 Western blot 分析,确认了没有蛋白质产物产生。(来源:J:125181)
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Exon 3 containing the translation initiation codon was replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis of brain lysate and postsynaptic density fraction. (J:125181)