Exon 3和4通过B6.129S4-Meox2tm1(cre)Sor小鼠的Cre介导重组被去除。预测的蛋白质产物包含信号序列但缺少邻近的123个外源性域氨基酸片段。作者认为这代表了一个轻度突变的等位基因。通过肾组织的RT-PCR实验确认了产生了一个缩短的转录本。(来源:J:125113)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/SvEv
Targeted
基因内删除
--
1
13
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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