Camk2a启动子驱动表达的是一个人类DISC1开放阅读框的剪切版本,它产生1到597个氨基酸。这个剪切蛋白被认为起着抑制作用。转基因在新生期表达优先,特别是在海马齿状回的锥体细胞中,且不干扰Disc1的内源基因表达。这是低表达的转基因品系。(来源:J:124683)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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插入
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1
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6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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