Exon 1被一个无启动子的β-geo cassette替换。通过 Western blot 用肝脏和肾脏组织检测,确认没有蛋白质产品产生。(来源:J:125009)
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Exon 1 was replaced by a promotorless beta-geo cassette. Absence of a protein product was confirmed by western blot using liver and kidney tissue. (J:125009)