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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(Col2a1-Npr2*B1)2Gar
Alias:
GC-B1
Tg(Col2a1-Npr2)2Gar
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基础信息
表型特征
文献报道
将一个整合了小鼠GC-B1亚型基因(在生长板软骨细胞中表达)的B-geo表达载体,通过驱动于Col2a1(II型胶原蛋白α1)启动子/增强子,导入了B6SJLF1胚胎中。(来源:J:94718)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3722687
(C57BL/6 x SJL)F1
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1
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1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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