将人类FGF2的cDNA,包括三个CUG密码子和AUG起始密码子的编码序列,置于磷酸甘油酸激酶的常规启动子驱动下。构建中包含了Pgk1的polyadenylation序列。这个构建被注入了FVB/N雌性核移植卵。通过Western blot确认了人类FGF2蛋白的产生。稳定拷贝数和转基因的可遗传性得到了鉴定,建立了线16。(引用:J:33064)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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