Exon 2被替换成一个核内的LacZ报告基因和诺卡因选择标记元件。在纯合小鼠的多种组织中,通过RT-PCR未检测到内源基因的表达。在纯合后期胚胎的肌间筋膜细胞中,观察到了LacZ染色,位于细胞核内。(来源:J:124184)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
插入,基因内删除
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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