第一外显子被β-半乳糖苷酶基因替换。LacZ可以再现内源性表达。通过RT-PCR和发育中骨的免疫荧光染色,未检测到RNA或蛋白质。对于同源小鼠的这两种邻近基因,Crmp1和Evc2的表达没有受到影响。(来源:J:124105)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1+
Targeted
插入,基因内删除
--
1
3
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部