一段反向插入的额外外显子4副本,包含lacZ编码序列和poly(A)信号,位于内源性外显子4上游。正常排列的loxP标记的诺卡因抗性基因座(neo)位于反向外显子4-lacZ的上游,两者间由一个12bp的V(D)J重组信号序列(RSS)分隔。内源性外显子4下游则有一个23bp的RSS。(参考文献: J:124224)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
插入
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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