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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Ctla4
tm1Yliu
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基础信息
表型特征
文献报道
人类的CTLA4基因的第二和第三外显子被插入到相应的位置,替换原有的第二和第三外显子。这些外显子编码了细胞外和跨膜区域。随后通过暂时的Cre表达,删除了floxed neo标记。(来源:J:123940)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3720741
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
9
2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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