LivLE6-DGAT1转基因是通过将人apoE基因的启动子和增强子序列与一个1.2kb的人类酰基-CoA:甘油二酯酰基转移酶1(DGAT1)的cDNA序列上游位置相结合设计的。这个转基因被注入了C57BL/6NHsd的受精卵中。在肝脏中检测到了DGAT1的过表达。(来源:J:124005)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NHsd
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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