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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
B9d2/Tgfb1
tm1Flv
Alias:
Tgfb1
f
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基础信息
表型特征
文献报道
在转化生长因子β1的启动子区域和exon 1以及B9蛋白域2的周围,插入了LoxP位点。载体中包含的条件性neo标记通过暂时的Cre表达被去除。(来源:J:123547)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3719581
129S6/SvEvTac
Targeted
插入
--
1
5
15
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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