Erf^tm1Gmav

A targeting vector replaced exons 2, 3 and part of exon 4, sequences that encode the DNA binding domain, with a floxed neomycin resistance cassette. Expression of a cre transgene carried by the parental ES cells removed the floxed neo cassette upon passage through the male germline. Northern blot confirmed absence of transcript in mutant mice. (J:123628)