Log In|Sign Up
中文
包含有floxed neo cassette的靶向载体通过同源重组在ES细胞中插入，随后在雄性嵌合小鼠传代时通过Cre介导的重组被移除，导致了homeodomain区域的删除。靶向发生在携带Tg(Prm-cre)70Og转基因的ES细胞中，该转基因在雄性生殖细胞中表达Cre重组酶。通过RT-PCR确认了内源性转录本的缺失。(来源：J:123638)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
