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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
基因编辑小鼠
Bcl6b
tm2Dent
Alias:
Bazf
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基础信息
表型特征
文献报道
一个编码124个C端氨基酸的区域被替换成pgk-neo cassette。这个删除区域包含了所有锌指氨基酸,因此目标基因通过替代转录失去了产生DNA结合蛋白的能力。RT-PCR证实了突变肺部没有转录本。(来源:J:123621)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
3719094
Not Specified
Targeted
插入,基因内删除
--
1
--
1
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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