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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
转基因模型
Tg(tetO-KLF4)32831Rup
Alias:
TRE-KLF4
TRE-KLF4
32831
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基础信息
表型特征
文献报道
人类Kruppel样因子基因KLF4的编码区域与一个含有四环素响应元件和人类细胞巨核病毒最小启动子的载体片段连接,形成了转录增强子。4.4kb的片段被注入到(C57BL/6 x SJL)F2雌性卵子中。(来源:J:96886)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
3717763
(C57BL/6 x SJL)F2
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插入
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1
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2
Phenotypes
Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes
References Literature
Title
PMID
Journal
Year
IF
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