设计了一种靶向载体,它将来自大鼠神经素1α的信号肽,随后是GFP的"翡翠"元件连接到exon1的氨基端,exon2两侧插入loxP位点,并在内含子2中插入一个由Flp标签的诺卡因抗性基因。实验后,通过western blot分析检测到了GFP融合蛋白的存在。(来源:J:122459)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
插入
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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