这个靶向载体包含了R229Q替换、2个沉默突变(A823G和T826A)、以及带有 floxed neo标签的EGFP,被插入到了特定的位置。之后,neo基因通过Cre介导的重组被去除了。(来源:J:122108)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv
Targeted
核苷酸替换
--
1
7
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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