在exon 2的上游插入了loxP位点和一个含氨苄青霉素抗性基因的弗里特-flanked序列,然后在exon 2下游1kb处插入了另一个loxP位点和EcoRI限制酶切点。通过Southern blotting和基因组PCR确认了目标插入的准确性。(来源:J:139846)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
2
28

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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