Cryge^No3

The locus contains a murine endogenous retroviral insertion (ERVK) in exon 3, with intact LTR sequences at both ends and a duplicated GGCGGC hexamer at the insertion site. The insertion is located after codon 142 of the ORF. The mutant transcript contains a normal N-terminal domain and a normal third motif, however, the fourth motif is truncated and would not be able to complete the C-terminal domain. RT-PCR confirmed expression of the mutant transcript. (J:63651, J:121863)