将孕激素受体Cre重组酶的cDNA插入到了人神经胶质纤维蛋白酸性蛋白(GFAP)启动子的调控下。在与报告小鼠杂交后,对4条表达Cre/PGR mRNA的线进行RU486诱导,结果没有一条显示出可诱导的重组酶活性,因此这些线被终止了。(来源:J:121777)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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插入
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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