这个转基因包含了9.5kb的鼠标水通道蛋白2基因5'上游区域,位于Cre重组酶序列(氨基酸端带有SV40核定位信号,羧基端带有来源于 HSV glycoprotein D 的11个氨基酸标签)的上游。水通道蛋白的调控序列驱动Cre在肾脏集合管和精子中的表达。(来源:J:104785)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x SJL)F2
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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