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中文
设计了一个转基因构建，包含在一段截短的 mouse CREB 结合蛋白（CBPdelta1，缺失1084-2441位氨基酸序列）的氨基端添加了一个FLAG标签，周围是人工内含子和5'端的起始和终止剪接点，以及3'端的SV40 polyadenylation信号。然后，这段FLAG-CBPD1序列被置于8.5kb的mouse CaMKIIalpha启动子下游。生成的13kb "CaMKIIalpha-FLAG-CBPdelta1"转基因被注入B6SJLF1胚胎的卵母细胞核中。这个截短产物的表达仅限于后天发育的海马、纹状体、杏仁核和皮质区域。（来源：J:121812）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
