从Pax6基因获得了三个特化的镜状结构元件,并将它们克隆到了Pax6的P0最小启动子上游。这个调节元件已知在前体性晶状体表皮以及周边头部表皮中驱动表达。外胚层增强子和启动子片段被用来驱动Cre重组酶和EGFP的表达,两者通过间隔增强子(IS)相连。实验小鼠饲养在FVB/N背景上。(来源:J:121794)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
IF
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