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中文
设计了一个靶向载体，目标是将IRES-cre-ER-neo插入到exon 4的第四外显子。这个插入导致了蛋白激酶A的磷酸化位点(S256)丢失，但推测的顶端定位信号保持不变。RT-PCR结果显示，exon 4下游序列没有表达，但上游包括cre重组酶的部分显示出转录。(来源：J:121445)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
